- CAS 1218-34-4
- Purity 99%
Location：Home > Pharmaceutical > N-Acetyl-L-tryptophan
Buy reliable Quality N-Acetyl-L-tryptophan 1218-34-4 raw material with Honest Price
- Molecular Formula: C13H14N2O3
- Molecular Weight: 246.266
- Appearance/Colour: solid
- Vapor Pressure: 1.32E-14mmHg at 25°C
- Melting Point: 186 °C
- Refractive Index: 1.645
- Boiling Point: 586.6 °C at 760 mmHg
- PKA: 3.65±0.10(Predicted)
- Flash Point: 308.6 °C
- PSA： 82.19000
- Density: 1.33g/cm3
- LogP: 1.69060
N-Acetyl-L-tryptophan(Cas 1218-34-4) Usage
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Safety Profile |
Moderately toxic by some routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOX,. |
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Definition |
ChEBI: A N-acetyl-L-amino acid that is the N-acetyl derivative of L-tryptophan. |
InChI:InChI=1/C13H14N2O3/c1-8(16)15-12(13(17)18)6-9-7-14-11-5-3-2-4-10(9)11/h2-5,7,12,14H,6H2,1H3,(H,15,16)(H,17,18)/t12-/m0/s1
1218-34-4 Relevant articles
Biosynthesis of violacein: Origins of hydrogen, nitrogen and oxygen atoms in the 2-pyrrolidone nucleus
Hoshino,Takano,Hori,Ogasawara
, p. 2733 - 2741 (1987)
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Oversby
, p. 1393 (1958)
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A fundamental study of amadori rearrangement products in reducing sugar-amino acid model system by electrospray ionization mass spectrometry and computation
Zhang,Ruan,Wang,Ruan,Shao,Aalhus,Juárez
, p. 2941 - 2944 (2014)
It is crucial to characterize Amadori re...
Reaction of vitamin e compounds with n-nitrosated tryptophan derivatives and its analytical use
Mueller, Karsten,Korth, Hans-Gert,De Groot, Herbert,Kirsch, Michael
, p. 7532 - 7542 (2007)
We recently showed that nitrosated trypt...
Comparison of HNO reactivity with tryptophan and cysteine in small peptides
Keceli, Gizem,Moore, Cathy D.,Toscano, John P.
, p. 3710 - 3713 (2014)
Recent discoveries of important pharmaco...
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Huang,Niemann
, p. 1541,1547 (1951)
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The biosynthetic pathway of crucifer phytoalexins and phytoanticipins: De novo incorporation of deuterated tryptophans and quasi-natural compounds
Pedras, M. Soledade C.,Okinyo-Owiti, Denis P.,Thoms, Ken,Adio, Adewale M.
, p. 1129 - 1138 (2009)
Although several biosynthetic intermedia...
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Shabica,Tishler
, p. 3251 (1949)
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Studies on acylase activity and microorganisms. VIII. Enzymatic hydrolysis of 6-N-benzoyl-L-lysine.
KAMEDA,TOYOURA,KIMURA,MATSUI
, p. 394 - 395 (1958)
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Kinetics and Mechanism of the Nitrosation of N-Acetyltryptophan and of the Denitrosation of N-Acetyl-N1-nitrosotryptophan
Castro, Albino,Iglesias, Emilia,Leis, J. Ramon,Pena, M. Elena,Tato, Jose Vazquez,Williams, D. Lyn H.
, p. 1165 - 1168 (1986)
Both the formation and the denitrosation...
Hydrogen/deuterium exchange of cross-linkable α-amino acid derivatives in deuterated triflic acid
Wang, Lei,Murai, Yuta,Yoshida, Takuma,Okamoto, Masashi,Masuda, Katsuyoshi,Sakihama, Yasuko,Hashidoko, Yasuyuki,Hatanaka, Yasumaru,Hashimoto, Makoto
, p. 1129 - 1134 (2014)
In this paper we report here a hydrogen/...
Crosslinking of imprinted proteases to maintain a tailor-made substrate selectivity in aqueous solutions
Peissker, Fabian,Fischer, Lutz
, p. 2231 - 2237 (1999)
A covalent method to keep imprinted prop...
Catecholamine-induced release of nitric oxide from N-nitrosotryptophan derivatives: A non-enzymatic method for catecholamine oxidation
Kytzia, Anna,Korth, Hans-Gert,De Groot, Herbert,Kirsch, Michael
, p. 257 - 267 (2006)
In recent years, interest in the physiol...
Influence of the Hetercyclic Ring on the Asymmetric Synthesis of β-Hetarylalanines by Homogeneous Catalytic Hydrogenation
Cativiela, Carlos,Mayoral, Jose A.,Melendez, Enrique,Oro, Luis A.,Pinillos, Maria T.,Uson, Rafael
, p. 2502 - 2504 (1984)
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Snyder,MacDonald
, p. 1257,1258 (1955)
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Structure-activity relationship studies of dipeptide-based hepsin inhibitors with Arg bioisosteres
Kwon, Hongmok,Ha, Hyunsoo,Jeon, Hayoung,Jang, Jaebong,Son, Sang-Hyun,Lee, Kiho,Park, Song-Kyu,Byun, Youngjoo
supporting information, (2020/12/25)
Hepsin is a type II transmembrane serine...
Tryptophan derivative and application thereof
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Paragraph 0192-0194, (2020/05/30)
The invention discloses a tryptophan der...
Reactivity of α-Amino Acids in the Reaction with Esters in Aqueous–1,4-Dioxane Media
Kochetova,Kustova,Kuritsyn
, p. 80 - 85 (2018/03/09)
The kinetics of the reaction of a series...
Synthesis and evaluation of oxindoles as promising inhibitors of the immunosuppressive enzyme indoleamine 2,3-dioxygenase 1
Paul, Saurav,Roy, Ashalata,Deka, Suman Jyoti,Panda, Subhankar,Srivastava, Gopal Narayan,Trivedi, Vishal,Manna, Debasis
, p. 1640 - 1654 (2017/08/22)
Indoleamine 2,3-dioxygenase 1 (IDO1) is ...
1218-34-4 Process route
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830-03-5
4-nitrophenol acetate
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73-22-3,27732-43-0,80206-30-0,27813-82-7
L-Tryptophan
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100-02-7,78813-13-5,89830-32-0
4-nitro-phenol
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1218-34-4
N-AcTrp
Conditions
| Conditions | Yield |
|---|---|
|
β‐cyclodextrin;
In
water; dimethyl sulfoxide;
at 25 ℃;
Rate constant;
Mechanism;
various conditions;
|
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65356-77-6
N-acetyl-L-triptophanyl-L-leucine amide
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687-51-4,13079-20-4,13366-40-0,15893-47-7
H-L-Leu-NH2
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1218-34-4
N-AcTrp
Conditions
| Conditions | Yield |
|---|---|
|
With
pH=7;
α-chymotrypsin;
In
water; ethyl acetate;
Equilibrium constant;
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1218-34-4 Upstream products
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56-23-5
tetrachloromethane
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108-24-7
acetic anhydride
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73-22-3
L-Tryptophan
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1218-34-4
N-acetyl-DL-tryptophan
1218-34-4 Downstream products
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2382-80-1
N-acetyl-L-tryptophane ethyl ester
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10022-82-9
D,L-1-Methyl-3,4-dihydro-β-carboline-3-carboxylic acid
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73-22-3
L-Tryptophan